The top amino-acid sequence in the banner is color coded (black for exposed and purple for buried) according to solvent accessibility in the X-ray structure (PDB 1who). The figure in the banner shows the X-ray structure, with exposed residues shown as gray surface and buried residues shown as purple spheres.

The bottom amino-acid sequence in the banner is color coded (black for exposed and green for buried) according to WESA prediction. The figure one the right shows the X-ray structure, with predicted exposed residues shown as gray surface and predicted buried residues shown as green spheres.